RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
MTO1
RNA ID
RNA Type
circRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
q-PCR; dual-lucimmunofluorescenceerase reporter assay etc.
Target
cMTO1
Pathway
NA
PubMed ID
Title
Circular RNA cMTO1 Promotes PTEN Expression Through Sponging miR-181b-5p in Liver Fibrosis
Year
2020
Function
"Cmto1 inhibits hsc activation, at least in part, through mir-181b-5p-mediated pten expression. Our results also suggest that cmto1 may be a novel therapeutic target in liver fibrosis."